SynfraCore
Synfracore
Start Learning
Navigation

Academies

Platform

RoadmapsLabsCertificationsInterviewPYQsAI AssistantCareer
Start Learning Free🗺️ Learning Roadmaps

ICD-10-CMPractice Q&A

Practice questions and model answers

💬
Verified by practitioners with 5+ years production experience· Updated 2025 · SynfraCore ICD-10-CM Team
Expert Content

ICD-10-CM Interview Questions & Advanced Coding

Beginner Questions

What is the difference between ICD-10-CM and ICD-10-PCS?

ICD-10-CM (Clinical Modification) is used to code diagnoses — what the patient has. It's used by all healthcare settings: physician offices, hospitals, outpatient facilities. ICD-10-PCS (Procedure Coding System) is used to code inpatient procedures — what was done to the patient in a hospital setting. PCS is only used for hospital inpatient claims. Outpatient procedures use CPT codes.


What does "code to the highest level of specificity" mean?

Always use the most specific code available that is supported by the documentation. If a code has 4, 5, 6, or 7 characters available, you must use all required characters. Choosing a less specific code when a more specific one exists is called "undercoding" and can result in claim denials and compliance issues. Example: M79.3 is "Panniculitis, unspecified" — if the documentation specifies the site, you must code to the site-specific code.


What is the significance of the first-listed diagnosis in outpatient coding?

For outpatient encounters, the first-listed diagnosis (not "principal diagnosis" — that term is only for inpatient) is the condition established to be chiefly responsible for the visit. In outpatient, do NOT code "probable" or "suspected" diagnoses — only code confirmed conditions or the symptom/sign. The first-listed diagnosis drives reimbursement and reporting.


Intermediate Questions

Explain the coding for diabetes mellitus with complications.

Diabetes codes are combination codes — one code captures both the diabetes type AND the complication. Key rules:

1.First identify the type: Type 1 (E10), Type 2 (E11), Other (E13), unspecified (E14)
2.The 5th character indicates the complication
3.Many complications require additional codes per "Use additional code" notes
4.Always code long-term insulin use (Z79.4) for Type 2 patients on insulin
E11.40  Type 2 DM with diabetic neuropathy, unspecified
E11.42  Type 2 DM with diabetic polyneuropathy
E11.649 Type 2 DM with hypoglycemia without coma
E11.65  Type 2 DM with hyperglycemia
E11.22  Type 2 DM with diabetic CKD, stage 3
        + N18.3 (CKD stage 3) — required additional code
E11.311 Type 2 DM with unspecified diabetic retinopathy with macular edema
        + Z79.4 if on insulin

What is the sequencing rule for sepsis?

Sepsis sequencing is a high-stakes coding scenario:

Sepsis as principal diagnosis:

Code first: the sepsis code (A41.9 Sepsis, unspecified, or specific organism)
Then: the underlying localized infection (e.g., J18.9 Pneumonia) as additional
Then: organ dysfunction codes if applicable (e.g., N17.9 Acute kidney failure)

Sepsis present on admission with a localized infection:

Sequence:
1. A41.01 Sepsis due to MRSA (or appropriate organism code)
2. J18.9  Pneumonia, unspecified (the source)
3. N17.9  Acute kidney injury (if present)

Severe sepsis: Code A41.xx + R65.20 (Severe sepsis without septic shock) OR R65.21 (with septic shock)

Critical rule: Never code "urosepsis" — it is not an accepted term. Query the physician.


When do you use Z codes?

Z codes (Z00-Z99) classify factors influencing health status when no illness or injury is present, or to provide additional information:

Category          Example codes
Encounters:       Z00.00  General adult exam, no abnormal findings
                  Z23     Immunization encounter
                  Z51.11  Antineoplastic chemotherapy

History:          Z85.3   Personal history of malignant neoplasm of breast
                  Z82.49  Family history of ischemic heart disease
                  Z87.891 Personal history of nicotine dependence

Status codes:     Z79.4   Long-term use of insulin
                  Z96.641 Presence of right artificial hip joint
                  Z99.11  Dependence on respirator [ventilator]

Screening:        Z12.31  Encounter for screening mammogram
                  Z13.220 Encounter for screening colonoscopy

Contact:          Z20.828 Contact with/exposure to COVID-19

Key rules for Z codes:

Some are principal/first-listed only
Some are additional codes only
Some can be either
Check the Tabular List for guidance on each specific code

Advanced Questions

Explain POA (Present on Admission) reporting.

POA indicates whether a diagnosis was present at the time of inpatient admission. CMS requires POA reporting on Medicare/Medicaid inpatient claims to distinguish hospital-acquired conditions (HACs) from pre-existing ones.

POA IndicatorMeaning

|--------------|---------|

**Y**Present at the time of admission
NNot present at time of admission
UDocumentation insufficient to determine
WProvider is unable to clinically determine
1Exempt from POA reporting (Z codes, injuries, etc.)

Why it matters: CMS does not pay the higher DRG rate for HACs that are not POA. For example, a pressure ulcer that developed during the hospital stay (N) will not increase reimbursement — but a pressure ulcer present on admission (Y) can be counted.


Code this complex case:

"65-year-old female admitted with acute exacerbation of COPD. She is a current smoker. She also has stage 3 CKD secondary to hypertension. Blood pressure is 168/94 on admission. Chest X-ray shows right lower lobe pneumonia. She is on insulin for her Type 2 diabetes."

Principal Diagnosis (caused the admission):
J44.1   COPD with acute exacerbation

Additional Diagnoses:
J18.1   Lobar pneumonia, unspecified organism (concurrent condition)
I12.9   Hypertensive chronic kidney disease with stage 1-4 CKD
N18.3   Chronic kidney disease, stage 3
E11.9   Type 2 diabetes mellitus without complications
F17.210 Nicotine dependence, cigarettes, uncomplicated
Z79.4   Long-term (current) use of insulin

Rationale:
- COPD exacerbation is principal (reason for admission)
- Pneumonia coded separately (documented concurrent condition)
- Hypertension + CKD → combination code I12.9 (assumed causal relationship)
- N18.3 required per I12.9 "Use additional code" instruction
- T2DM without specified complications — documentation doesn't specify
- Current smoker coded with tobacco dependence category
- Insulin use required per diabetes guidelines
- Blood pressure elevation captured by I12.9 (hypertension always included)

What is the difference between Excludes1 and Excludes2?

This is one of the most tested concepts:

Excludes1 — Mutually exclusive. The two conditions CANNOT occur together (they are the same condition). Do NOT use both codes.

Example:
F41.0 Panic disorder [episodic paroxysmal anxiety]
  Excludes1: panic disorder with agoraphobia (F40.01)
→ A patient CANNOT have both F41.0 AND F40.01

Excludes2 — The excluded condition is NOT included in this code, but may coexist. CAN use both codes if both conditions are documented.

Example:
J44 COPD
  Excludes2: asthma (J45.-)
→ A patient CAN have both COPD (J44.x) AND Asthma (J45.x)
   Code both if both are documented and treated

Memory trick:

Excludes1 = 1 code only (can't use together)
Excludes2 = can use 2 codes (both acceptable)

Coding Practice Cases

Case 1: Patient with chest pain, rule out MI. Tests negative, final diagnosis: Chest pain due to GERD.

Answer: R07.9 Chest pain, unspecified is WRONG. The final diagnosis is GERD (K21.9). Code the confirmed diagnosis, not the symptom. The "rule out MI" is not coded — outpatient rule.

Case 2: Patient presents with infected diabetic foot ulcer, Type 2 DM, insulin-dependent.

E11.621  Type 2 DM with foot ulcer
L97.509  Non-pressure chronic ulcer of other part of unspecified foot, unspecified severity
L08.9    Local infection of the skin and subcutaneous tissue (if cellulitis: L03.115)
Z79.4    Long-term use of insulin

Case 3: Outpatient encounter. Documentation: "Probable UTI."

Answer: Do NOT code N39.0 (UTI) for outpatient. Code the symptom instead: R30.0 (Dysuria), R35.0 (Frequency), or whatever symptom brought the patient in. "Probable" diagnoses are INPATIENT only.

Share:
Join our Community
Health & wellness tips, coding Q&A — join learners growing together
Up Next
🏆
ICD-10-CMCertification
Exam guides, practice questions, and prep strategies
Also Worth Exploring
← Back to all ICD-10-CM modules
ProjectsCertification