NEET Chemistry Advanced Topics
Coordination Compounds
IUPAC NOMENCLATURE:
1. Name cationic complex then anionic part (like ionic compounds)
2. Within complex: anionic ligands first, then neutral, then metal + oxidation state
Common ligands and names:
Cl⁻ = chlorido | F⁻ = fluorido | CN⁻ = cyanido | OH⁻ = hydroxido
NH₃ = ammine | H₂O = aqua | CO = carbonyl | NO = nitrosyl
en = ethylenediamine | EDTA⁴⁻ = ethylenediaminetetraacetato
Prefixes: 2=di, 3=tri, 4=tetra, 5=penta, 6=hexa
For polydentate: bis, tris, tetrakis (to avoid confusion)
Examples:
[Co(NH₃)₆]Cl₃ = hexaamminecobalt(III) chloride
K₄[Fe(CN)₆] = potassium hexacyanoferrate(II)
[Pt(en)₂Cl₂] = dichlorobis(ethylenediamine)platinum(IV)
BONDING THEORIES:
Valence Bond Theory (VBT):
Inner orbital complexes: (n-1)d used → low spin (diamagnetic if all paired)
Outer orbital complexes: nd used → high spin (paramagnetic)
[Fe(CN)₆]⁴⁻: d²sp³ hybridization (inner, diamagnetic)
[Fe(H₂O)₆]²⁺: sp³d² hybridization (outer, paramagnetic)
Crystal Field Theory (CFT):
Strong field (large Δ): CN⁻, CO → low spin | Weak field (small Δ): F⁻, H₂O → high spin
Spectrochemical series: I⁻ < Br⁻ < Cl⁻ < F⁻ < OH⁻ < H₂O < en < NO₂⁻ < CN⁻ < CO
ISOMERISM:
Structural: ionization, hydrate, linkage, coordination isomerism
Stereoisomers: geometric (cis-trans) and optical
Square planar [MA₂B₂]: cis and trans possible | [MABCD]: 3 geometric isomers
Octahedral [MA₄B₂]: cis (same side) and trans (opposite) | [MA₃B₃]: fac and merBiomolecules
CARBOHYDRATES:
General formula: Cₙ(H₂O)ₙ
Monosaccharides: glucose (C₆H₁₂O₆), fructose, galactose
Glucose: open chain (CHO-CHOH-...CH₂OH) | α and β forms in ring
Disaccharides: sucrose (glucose+fructose, non-reducing)
maltose (glucose+glucose, reducing) | lactose (glucose+galactose)
Polysaccharides: starch (amylose+amylopectin) | cellulose | glycogen
PROTEINS:
Amino acids: H₂N-CHR-COOH | 20 standard amino acids
Peptide bond: between -COOH and -NH₂ with loss of water
Protein structure:
1°: amino acid sequence | 2°: α-helix or β-sheet (H-bonds)
3°: overall 3D shape | 4°: association of subunits
Denaturation: disruption of 2°,3°,4° structure (not 1°)
NUCLEIC ACIDS:
Nucleotide = phosphate + sugar + base
DNA: deoxyribose sugar | A-T (2 H-bonds), G-C (3 H-bonds)
RNA: ribose sugar | U instead of T (in RNA, no T)
Watson-Crick: double helix, anti-parallel, complementary base pairingStudy Resources
•NCERT Chemistry Chapter 9 (Coordination) and 14 (Biomolecules) — read 3 times
•JD Lee Concise Inorganic Chemistry — coordination chemistry deep dive
•VK Jaiswal NEET Organic — mechanisms for advanced organic questions
•NEET 2020-2024 papers — coordination always has 3-5 questions

